Article
Genome-wide two-marker linkage disequilibrium mapping of quantitative trait loci.
BMC genetics - 8 Feb 2014
Yang Jie, Zhu Wei, Chen Jiansong, Zhang Qiao, Wu Song
Abstract excerpt
BACKGROUND: In a natural population, the alleles of multiple tightly linked loci on the same chromosome co-segregate and are passed non-randomly from generation to generation. Capitalizing on this phenomenon, a group of mapping methods, commonly referred to as the linkage disequilibrium-based mapping (LD mapping), have been developed recently for detecting genetic associations. However, most current LD mapping...
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