Article
Involvment of c-Abl in the radiation-induced inhibition of myoblast differentiation.
International journal of radiation biology - 1 Oct 2004
Hoerth E, Kodym R
Abstract excerpt
PURPOSE: While radiation-induced differentiation is common in many cell types it has been shown (Ikeda et al. 2000) that irradiation inhibits differentiation of murine myoblast cell line C2C12. To investigate the mechanisms responsible for this phenomenon we looked into the role of the non-receptor tyrosine kinase c-Abl. MATERIAL AND METHODS: C-Abl activity was determined using an immune-complex kinase assay and...
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