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Article

Role of c-Myc on erythroid differentiation.

The Tohoku journal of experimental medicine - 1 Oct 1992

Ohmori Y, Tanabe J, Terashima M, Shoji W, Takada S, Obinata M

Abstract excerpt

In the early event of the induction of mouse erythroleukemia (MEL) cell differentiation, c-myc mRNA levels show a biphasic change. The elevated expression of a transfected c-myc gene inhibits the commitment and differentiation of MEL cell transformants. In the present work, we have introduced human c-myc mutants into MEL cells under the inducible promoter to define the functional domains of c-Myc involved in...

Topics

Animals
Biopolymers
Cell Differentiation
Genes, myc
Humans
Leukemia, Erythroblastic, Acute
Mice
Mutation
Phenotype
Tumor Cells, Cultured

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1306305
DOI: 10.1620/tjem.168.203

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1306305-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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