Article
Overexpression of DNA methyltransferase in myoblast cells accelerates myotube formation.
European journal of biochemistry - 15 Jul 1995
Takagi H, Tajima S, Asano A
Abstract excerpt
We overexpressed mouse DNA methyltransferase in murine C2C12 myoblast cells and tested the isolated clones for their ability to differentiate. Significant numbers of the clones showed distinct myotubes 24 h after the isolated transformants had been induced to differentiate, whereas the parent C2C...
Topics
- Animals
- Cell Differentiation
- Cell Line
- Creatine Kinase
- Cytosine
- DNA
- DNA Modification Methylases
- DNA, Complementary
- Enzyme Induction
- Gene Expression Regulation
- Immunoelectrophoresis
- Methylation
- Mice
- Muscles
- MyoD Protein
- Myosins
- Phenotype
- Transfection