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Article

Overexpression of DNA methyltransferase in myoblast cells accelerates myotube formation.

European journal of biochemistry - 15 Jul 1995

Takagi H, Tajima S, Asano A

Abstract excerpt

We overexpressed mouse DNA methyltransferase in murine C2C12 myoblast cells and tested the isolated clones for their ability to differentiate. Significant numbers of the clones showed distinct myotubes 24 h after the isolated transformants had been induced to differentiate, whereas the parent C2C12 cells did not form myotubes at this time point. Transfection of the vacant vector or the plasmid containing the...

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PMID: 7635139
DOI: 10.1111/j.1432-1033.1995.tb20698.x

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