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Article

Inhibition of myogenic differentiation in myoblasts expressing a truncated type II TGF-β receptor

1 May 1994

Abstract excerpt

Transforming growth factor-beta (TGF-beta) is thought to play a role in mesenchymal cell development and, specifically, in muscle differentiation, yet its precise role in the latter process remains unclear. TGF-beta has been shown to both inhibit and induce myoblast maturation in vitro, depending on the culture conditions. Whether the type I or type II TGF-beta receptor mediates the various TGF-beta effects on...

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PMID: 8026322
DOI: 10.1242/dev.120.5.1085

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