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Article

Micronuclei in EM9 cells expressing polymorphic forms of human XRCC1.

Cancer letters - 18 Apr 2005

Qu Tianli, Morii Eiichi, Oboki Keisuke, Lu Yuquan, Morimoto Kanehisa

Abstract excerpt

X-ray repair cross-complementing gene 1 (XRCC1) is involved in base excision repair (BER) through interaction with other BER enzymes, and polymorphisms in XRCC1 appear to increase the risk of various cancers. We evaluated how three XRCC1 polymorphisms, Arg194Trp, Arg280His and Arg399Gln, affect the extent of DNA damage and repair using the micronucleus assay. XRCC1 cDNAs containing the wild-type sequence and the...

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Source

Identifiers

PMID: 15797631
DOI: 10.1016/j.canlet.2004.08.013

Genes

XRCC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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