Article
DNA mismatch correction by Very Short Patch repair may have altered the abundance of oligonucleotides in the E. coli genome.
Nucleic acids research - 11 Apr 1992
Bhagwat A S, McClelland M
Abstract excerpt
A base mismatch correction process in E. coli K-12 called Very Short Patch (VSP) repair corrects T:G mismatches to C:G when found in certain sequence contexts. Two of the substrate mismatches (5'-CTWGG/3'-GGW'CC; W = A or T) occur in the context of cytosine methylation in DNA and reduce the mutagenic effects of 5-methylcytosine deamination to thymine. However, VSP repair is also known to repair T:G mismatches...
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