Article
DNA mismatch correction by Very Short Patch repair may have altered the abundance of oligonucleotides in the E. coli genome.
Nucleic acids research - 11 Apr 1992
Bhagwat A S, McClelland M
Abstract excerpt
A base mismatch correction process in E. coli K-12 called Very Short Patch (VSP) repair corrects T:G mismatches to C:G when found in certain sequence contexts. Two of the substrate mismatches (5'-CTWGG/3'-GGW'CC; W = A or T) occur in the context of cytosine methylation in DNA and reduce the mutag...
Topics
- 5-Methylcytosine
- Base Composition
- Cytidine
- Cytosine
- DNA Repair
- DNA, Bacterial
- DNA-Cytosine Methylases
- Escherichia coli
- Genome, Bacterial
- Markov Chains
- Mutation
- Oligodeoxyribonucleotides
- Saccharomyces cerevisiae
- Thymidine
