Article
A gene required for very short patch repair in Escherichia coli is adjacent to the DNA cytosine methylase gene.
Journal of bacteriology - 1 Aug 1990
Sohail A, Lieb M, Dar M, Bhagwat A S
Abstract excerpt
Deamination of 5-methylcytosine in DNA results in T/G mismatches. If unrepaired, these mismatches can lead to C-to-T transition mutations. The very short patch (VSP) repair process in Escherichia coli counteracts the mutagenic process by repairing the mismatches in favor of the G-containing stran...
Topics
- Amino Acid Sequence
- Base Sequence
- DNA (Cytosine-5-)-Methyltransferases
- DNA Repair
- DNA-Cytosine Methylases
- Endodeoxyribonucleases
- Escherichia coli
- Escherichia coli Proteins
- Genes, Bacterial
- Genetic Linkage
- Molecular Sequence Data
- Phenotype
- Restriction Mapping
- Sequence Homology, Nucleic Acid
