Article
Very-short-patch repair in Escherichia coli requires the dam adenine methylase.
Journal of bacteriology - 1 Jun 2001
Bell D C, Cupples C G
Abstract excerpt
Strains of Escherichia coli which lack the dam-encoded adenine methylase are mutators due to a reduction in the efficiency of postreplication mismatch repair. In this study, we show that Dam(-) strains are also defective in very-short-patch repair, the system which corrects T/G mismatches arising from the deamination of 5-methylcytosine. This defect is associated with decreased levels of Vsr, the endonuclease...
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