Article
DNA repair: getting past a lesion - at a cost.
Current biology : CB - 3 Dec 1998
Bridges B A
Abstract excerpt
Bacteria survive many types of synthesis-blocking DNA lesion by inducing a number of proteins that enable their polymerases to synthesize past a lesion, albeit at the cost of an increased mutation rate. This process has now been convincingly achieved in vitro, opening the way to a fuller understa...
Topics
- Bacteria
- Bacterial Proteins
- DNA Damage
- DNA Polymerase III
- DNA Repair
- DNA, Bacterial
- DNA-Directed DNA Polymerase
- Escherichia coli Proteins
- Holoenzymes
- Mutation
- Rec A Recombinases
- SOS Response, Genetics