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Article

The genetic variation of CCR5, CXCR4 and SDF-1 in three Chinese ethnic populations.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jul 2012

Liu Yanyan, Liu Feng-Liang, He Yanqin, Li Liming, Li Shilin, Zheng Yong-Tang, Wang Hongyan, Gong Xiaohong

Abstract excerpt

The chemokine receptors and ligand CCR5, CXCR4 and SDF-1 play important roles in the entry of HIV-1 into host cells. Genetic polymorphisms such as CCR5-Δ32 and SDF-1 3'A have been reported to be associated with HIV-1 susceptibility and the progression of AIDS. Considering the remarkable difference in CCR5-Δ32 allele frequency among worldwide populations, we aimed to survey the genetic variations in CCR5, CXCR4...

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Source

Identifiers

PMID: 22554649
DOI: 10.1016/j.meegid.2012.03.009

Genes

CCR5
CXCR4
MAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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