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Article

Polymorphism in the CCR5 gene promoter and HIV-1 infection in North Indians.

Human immunology - 1 May 2007

Kaur Gurvinder, Singh P, Rapthap C C, Kumar N, Vajpayee M, Sharma S K, Wanchu A, Mehra N K

Abstract excerpt

The clinical course and outcome of human immunodeficiency virus-1 (HIV-1) infection are highly variable among individuals. CCR5 is the primary coreceptor that mediates entry of HIV-1 (R5) into permissive host cells. In this study, five SNPs (59029G/A, 59353T/C, 59356C/T, 59402A/G, and 59653C/T) in the promoter region and a deletion of 32 bp (Delta32) in the CCR5 gene were evaluated in 180 chronically...

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Source

Identifiers

PMID: 17462514
DOI: 10.1016/j.humimm.2007.01.016

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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