Article
[Single nucleotide polymorphism loci of HIV-1 coreceptor CCR5 gene in Chinese Han people].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Feb 2003
Liu Ming-xu, Wang Fu-sheng, Hong Wei-guo, Wang Bo, Jin Lei, Lei Zhou-yun, Hou Jing
Abstract excerpt
OBJECTIVE: To investigate the single nucleotide polymorphism(SNP) loci of HIV-1 coreceptor CCR5 gene in Chinese Han people. METHODS: The coding region of CCR5 was amplified using 2 pairs of primers and the PCR products of all 42 healthy subjects were sequenced by 4 different primers. The results of sequencing were analyzed by DNAstar in search of SNP loci. RESULTS: Six SNP loci were discovered in the coding...
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