Article
Identification of multiple nuclear export sequences in Fanconi anemia group A protein that contribute to CRM1-dependent nuclear export.
Human molecular genetics - 15 May 2005
Ferrer Miriam, Rodríguez Jose A, Spierings Ellen A, de Winter Johan P, Giaccone Giuseppe, Kruyt Frank A E
Abstract excerpt
The Fanconi anemia (FA) pathway plays an important role in maintaining genomic stability, and defects in this pathway cause cancer susceptibility. The FA proteins have been found to function primarily in a nuclear complex, although a cytoplasmic localization and function for several FA proteins has also been reported. In this study, we investigated the possibility that FANCA, FANCC and FANCG are subjected to...
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