Article
An alternative domain containing a leucine-rich sequence regulates nuclear cytoplasmic localization of protein 4.1R.
The Journal of biological chemistry - 24 Jan 2003
Luque Carlos M, Pérez-Ferreiro Carmen M, Pérez-Gonzalez Alicia, Englmeier Ludwig, Koffa Maria D, Correas Isabel
Abstract excerpt
In red blood cells, protein 4.1 (4.1R) is an 80-kDa protein that stabilizes the spectrin-actin network and anchors it to the plasma membrane. The picture is more complex in nucleated cells, in which many 4.1R isoforms, varying in size and intracellular location, have been identified. To contribute to the characterization of signals involved in differential intracellular localization of 4.1R, we have analyzed the...
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