Article
E2F4 is exported from the nucleus in a CRM1-dependent manner.
Molecular and cellular biology - 1 Feb 2001
Gaubatz S, Lees J A, Lindeman G J, Livingston D M
Abstract excerpt
E2F is a family of transcription factors required for normal cell cycle control and for cell cycle arrest in G1. E2F4 is the most abundant E2F protein in many cell types. In quiescent cells, it is localized to the nucleus, where it is bound to the retinoblastoma-related protein p130. During entry into the cell cycle, the protein disappears from the nucleus and appears in the cytoplasm. The mechanism by which this...
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