Article
Analysis of families in the multiple autoimmune disease genetics consortium (MADGC) collection: the PTPN22 620W allele associates with multiple autoimmune phenotypes.
American journal of human genetics - 1 Apr 2005
Criswell Lindsey A, Pfeiffer Kirsten A, Lum Raymond F, Gonzales Bonnie, Novitzke Jill, Kern Marlena, Moser Kathy L, Begovich Ann B, Carlton Victoria E H, Li Wentian, Lee Annette T, Ortmann Ward, Behrens Timothy W, Gregersen Peter K
Abstract excerpt
Autoimmune disorders constitute a diverse group of phenotypes with overlapping features and a tendency toward familial aggregation. It is likely that common underlying genes are involved in these disorders. Until very recently, no specific alleles--aside from a few common human leukocyte antigen class II genes--had been identified that clearly associate with multiple different autoimmune diseases. In this study,...
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