Article
The Natural Killer Complex Regulates Severe Malarial Pathogenesis and Influences Acquired Immune Responses toPlasmodium bergheiANKA
22 Mar 2005
Abstract excerpt
The natural killer complex (NKC) is a genetic region of highly linked genes encoding several receptors involved in the control of NK cell function. The NKC is highly polymorphic, and allelic variability of various NKC loci has been demonstrated in inbred mice. Making use of BALB.B6-Cmv1r congenic mice, in which the NKC from disease-susceptible C57BL/6 mice has been introduced into the disease-resistant BALB/c...
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