Article
The contribution of natural killer complex loci to the development of experimental cerebral malaria.
PloS one - 1 Jan 2014
Hansen Diana S, Ryg-Cornejo Victoria, Ioannidis Lisa J, Chiu Chris Y, Ly Ann, Nie Catherine Q, Scalzo Anthony A, Schofield Louis
Abstract excerpt
BACKGROUND: The Natural Killer Complex (NKC) is a genetic region of highly linked genes encoding several receptors involved in the control of NK cell function. The NKC is highly polymorphic and allelic variability of various NKC loci has been demonstrated in inbred mice, providing evidence for NKC haplotypes. Using BALB.B6-Cmv1r congenic mice, in which NKC genes from C57BL/6 mice were introduced into the BALB/c...
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