Article
Widespread natural variation in murine natural killer T-cell number and function.
Immunology - 1 Nov 2008
Rymarchyk Stacia L, Lowenstein Hayden, Mayette Jana, Foster Samantha R, Damby David E, Howe Isaac W, Aktan Idil, Meyer Russell E, Poynter Matthew E, Boyson Jonathan E
Abstract excerpt
Natural killer T (NKT) cells comprise a novel T-lymphocyte subset that can influence a wide variety of immune responses through their ability to secrete large amounts of a variety of cytokines. Although variation in NKT-cell number and function has been extensively studied in autoimmune disease-prone mice, in which it has been linked to disease susceptibility, relatively little is known of the natural variation...
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