NK Cells Stimulate Recruitment of CXCR3+ T Cells to the Brain during Plasmodium berghei -Mediated Cerebral Malaria

Abstract excerpt

NK cells are cytotoxic lymphocytes that also secrete regulatory cytokines and can therefore influence adaptive immune responses. NK cell function is largely controlled by genes present in a genomic region named the NK complex. It has been shown that the NK complex is a genetic determinant of murine cerebral malaria pathogenesis mediated by Plasmodium berghei ANKA. In this study, we show that NK cells are required...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Complement system in diseases
• Share to Immune Cell Function and Interaction
• Share to Malaria Research and Control