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Article

Presence of allelic loss and PTEN mutations in malignant gliomas from Malay patients.

The Medical journal of Malaysia - 1 Oct 2004

Zainuddin N, Jaafar H, Isa M N, Abdullah J M

Abstract excerpt

Loss of heterozygosity (LOH) on several loci and mutations on PTEN tumor suppressor gene (10q23.3) occur frequently in sporadic gliomas. We have performed polymerase chain reaction (PCR)-LOH analysis using microsatellite markers and single-stranded conformational polymorphism (SSCP) analysis to determine the incidence of allelic losses on chromosome 10q, 9p, 17p and 13q and mutations of exons 5, 6 and 8 of the...

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Source

Identifiers

PMID: 15779579

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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