Article
Loss of heterozygosity on chromosomes 10q, 9p, 17p and 13q in malays with malignant glioma.
Neurological research - 1 Jan 2004
Zainuddin Norafiza, Jaafart Hasnan, Isa Mohd Nizam, Abdullah Jafri Malin
Abstract excerpt
Recent advances in neuro-oncology have revealed different pathways of molecular oncogenesis in malignant gliomas including loss of heterozygosity on chromosomal regions harboring tumor suppressor genes. In the present study, we performed polymerase chain reaction-loss of heterozygosity (PCR-LOH) analysis using microsatellite markers to identify loss of heterozygosity on chromosomes 10q, 9p, 17p and 13q in the...
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