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Article

PTEN mutations in malignant gliomas and their relation with meningeal gliomatosis.

Journal of neuro-oncology - 1 May 2001

Izumoto S, Ohnishi T, Kanemura H, Arita N, Maruno M, Moriuchi T, Suzuki S, Yoshimine T

Abstract excerpt

A putative tumor suppressor, the PTEN gene at chromosome 10q23. was identified and found to be mutated in many different human tumors. PTEN was recently found to be also involved in focal cell adhesion and cell migration. To identify the role of PTEN gene in malignant gliomas. we used PCR-SSCP and direct sequencing methods to examine 44 malignant gliomas comprising 29 cases without and 15 cases with meningeal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11678426
DOI: 10.1023/a:1011839920176

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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