Article
Deletion mapping of chromosome 10 in human glioma.
Japanese journal of cancer research : Gann - 1 Apr 1996
Sonoda Y, Murakami Y, Tominaga T, Kayama T, Yoshimoto T, Sekiya T
Abstract excerpt
We analyzed DNAs from 35 gliomas (27 malignant, grades III and IV; 8 less malignant, grades I and II) for loss of heterozygosity (LOH) using microsatellite sequences on chromosome 10 as polymorphic markers. An LOH was found in 8 of 11 (73%) glioblastomas (grade IV) and 4 of 16 (25%) grade III gliomas, but not in the less malignant types. We detected three commonly deleted regions. One was located in a telomeric...
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