Loss of heterozygosity of chromosome 10p in human gliomas.

doi:10.1006/geno.1996.0277

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Article

Loss of heterozygosity of chromosome 10p in human gliomas.

Genomics - 1 Jun 1996

Kimmelman A C, Ross D A, Liang B C

Abstract excerpt

Molecular loss of heterozygosity studies on human gliomas have shown several regions on chromosome 10 frequently deleted in higher grade tumors, suggesting that chromosome 10 may contain several tumor suppressor genes. We assessed loss of heterozygosity with microsatellite markers in 20 gliomas,...

Topics

Astrocytoma
Brain Neoplasms
Chromosome Deletion
Chromosome Mapping
Chromosomes, Human, Pair 10
DNA, Satellite
Genetic Markers
Glioma
Humans
Phenotype
Polymerase Chain Reaction

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