Article
[Immunohistochemical study of p53 mutation and p16, p14 alterations encoded by INK4a-ARF in mucin-hypersecreting bile duct tumor].
The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi - 1 Mar 2005
Kim Hong Ja, Kim Myung Hwan, Song Moon Hee, Song Dong Eun, Yu Eunsil
Abstract excerpt
BACKGROUND/AIMS: Mucin-hypersecreting bile duct tumor is rare, and has an unusual histologic characteristic of having various degrees of cellular atypia ranging from dysplasia to invasive carcinoma in the same specimen. To gain insight into the role of p16, p14 and p53 in the carcinogenic process of bile duct tumor, we analyzed the expression status of these proteins in mucin-hypersecreting bile duct tumor....
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