Article
Tumorigenesis and phenotypic characteristics of mucin-producing bile duct tumors: an immunohistochemical approach.
Journal of hepato-biliary-pancreatic sciences - 1 May 2010
Nakanuma Yasuni, Zen Yoh, Harada Kenichi, Ikeda Hiroko, Sato Yasunori, Uehara Takeshi, Sasaki Motoko
Abstract excerpt
Intraductal papillary neoplasm of the bile duct (IPNB) is characterized by exophytic proliferation of neoplastic epithelial cells with fibrovascular stalks in bile duct lumen, mucin hypersecretion, and considerable dilatation or multilocular changes of the affected bile ducts. A mucin-producing bile duct tumor is an IPNB with excessive mucin production and clinical symptoms. Herein, the phenotypes as well as the...
Topics
- Adenocarcinoma, Mucinous
- Bile Duct Neoplasms
- CDX2 Transcription Factor
- Cadherins
- Carcinoma, Ductal
- Carcinoma, Papillary
- Cholangiocarcinoma
- Cyclin D1
- Disease Progression
- Homeodomain Proteins
- Humans
- Immunohistochemistry
- Keratin-20