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Article

Alteration of the p14(ARF) gene and p53 status in human hepatocellular carcinomas.

Journal of gastroenterology - 1 Jan 2004

Ito Teruaki, Nishida Naoshi, Fukuda Yoshihiro, Nishimura Takafumi, Komeda Toshiki, Nakao Kazuwa

Abstract excerpt

BACKGROUND: The INK4a/ARF locus encodes p16INK4a and p14ARF, both of which are crucial for two tumor suppressor pathways, retinoblastoma (RB)/p16INK4a and p53/ARF. Inactivation of RB/p16INK4a was frequently reported, but alterations of the p14ARF gene in hepatocellular carcinoma (HCC) in the Japanese population have been insufficiently analyzed. METHODS: To determine the role of p53/ARF alteration in...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15168247
DOI: 10.1007/s00535-003-1302-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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