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Article

Alterations of p16 and prognosis in biliary tract cancers from a population-based study in China.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Mar 2004

Ueki Takashi, Hsing Ann W, Gao Yu-Tang, Wang Bing-Sheng, Shen Ming-Chang, Cheng Jiarong, Deng Jie, Fraumeni Joseph F, Rashid Asif

Abstract excerpt

PURPOSE: Biliary tract cancer is an uncommon malignancy with a poor survival rate. We evaluated p16 gene alteration as a prognostic marker for this disease. EXPERIMENTAL DESIGN: We studied p16 gene alterations by sequencing, methylation, and loss of heterozygosity of chromosome 9p in 118 biliary tract carcinomas, including 68 gallbladder cancers, 33 extrahepatic bile duct cancers, and 17 ampullary cancers....

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PMID: 15014024
DOI: 10.1158/1078-0432.ccr-1137-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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