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Article

[Genetic alterations in gallbladder carcinoma: a review].

Nihon Geka Gakkai zasshi - 1 Oct 1998

Yokoyama N, Watanabe H, Ajioka Y, Nishikura K, Date K, Kijima H, Shirai Y, Hatakeyama K

Abstract excerpt

Earlier evidence suggests that gallbladder carcinoma (GBC) has three carcinogenic pathways; de novo development; adenoma-carcinoma sequence; and hyperplasia-carcinoma sequence associated with an anomalous arrangement of the pancreaticobiliary duct (AAPBD). We review gene abnormalities in GBC reported to date. p53 mutation and its protein overexpression are frequently observed in de novo carcinoma and GBC with...

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PMID: 9866832

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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