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Article

Architecture of the yeast Elongator complex.

EMBO reports - 1 Feb 2017

Dauden Maria I, Kosinski Jan, Kolaj-Robin Olga, Desfosses Ambroise, Ori Alessandro, Faux Celine, Hoffmann Niklas A, Onuma Osita F, Breunig Karin D, Beck Martin, Sachse Carsten, Séraphin Bertrand, Glatt Sebastian, Müller Christoph W

Abstract excerpt

The highly conserved eukaryotic Elongator complex performs specific chemical modifications on wobble base uridines of tRNAs, which are essential for proteome stability and homeostasis. The complex is formed by six individual subunits (Elp1-6) that are all equally important for its tRNA modification activity. However, its overall architecture and the detailed reaction mechanism remain elusive. Here, we report the...

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Identifiers

PMID: 27974378
DOI: 10.15252/embr.201643353
PMCID: PMC5286394

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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