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Article

Phosphorylation of Elp1 by Hrr25 is required for elongator-dependent tRNA modification in yeast.

PLoS genetics - 1 Jan 2015

Abdel-Fattah Wael, Jablonowski Daniel, Di Santo Rachael, Thüring Kathrin L, Scheidt Viktor, Hammermeister Alexander, Ten Have Sara, Helm Mark, Schaffrath Raffael, Stark Michael J R

Abstract excerpt

Elongator is a conserved protein complex comprising six different polypeptides that has been ascribed a wide range of functions, but which is now known to be required for modification of uridine residues in the wobble position of a subset of tRNAs in yeast, plants, worms and mammals. In previous work, we showed that Elongator's largest subunit (Elp1; also known as Iki3) was phosphorylated and implicated the yeast...

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Identifiers

PMID: 25569479
DOI: 10.1371/journal.pgen.1004931
PMCID: PMC4287497

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Phosphorylation of Elp1 by Hrr25 is required for elongator-dependent tRNA modification in yeast.PMID 25569479Read ↗

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