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Article

Characterization of mutations associated with the adaptation of a low-pathogenic H5N1 avian influenza virus to chicken embryos.

Veterinary microbiology - 23 Mar 2013

Kim Il-Hwan, Kwon Hyuk-Joon, Choi Jun-Gu, Kang Hyun-Mi, Lee Youn-Jeong, Kim Jae-Hong

Abstract excerpt

Migratory waterfowls are the most common reservoir for avian influenza virus (AIV), thus viral adaptation is required for efficient replication in land fowls. To date, low pathogenic (LP) H5 subtype AIVs have been isolated from migratory waterfowls, and the adaptation of these viruses to land fowls might lead to the generation of highly pathogenic AIVs. Thus, A/wild duck/Korea/50-5/2009 (H5N1) LPAIV was passaged...

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PMID: 23211427
DOI: 10.1016/j.vetmic.2012.10.034

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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