Article
Genetic and phenotypic analysis of reassortants of high growth and low growth strains of influenza B virus.
Vaccine - 8 Sept 2003
Vodeiko G M, McInnis J, Chizhikov V, Levandowski R A
Abstract excerpt
The yield of influenza virus in eggs is critical to influenza vaccine production and availability, but the contribution of specific genes to the growth properties of influenza B viruses is not well understood. Influenza B/Beijing/184/93 and B/Shangdong/7/97 were chosen for study because B/Shangdong/7/97 replicated to several fold higher titers in eggs than B/Beijing/184/93 as demonstrated by hemagglutination...
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