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Article

Single PA mutation as a high yield determinant of avian influenza vaccines.

Scientific reports - 13 Jan 2017

Lee Ilseob, Il Kim Jin, Park Sehee, Bae Joon-Yong, Yoo Kirim, Yun Soo-Hyeon, Lee Joo-Yeon, Kim Kisoon, Kang Chun, Park Man-Seong

Abstract excerpt

Human infection with an avian influenza virus persists. To prepare for a potential outbreak of avian influenza, we constructed a candidate vaccine virus (CVV) containing hemagglutinin (HA) and neuraminidase (NA) genes of a H5N1 virus and evaluated its antigenic stability after serial passaging in...

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Identifiers

PMID: 28084423
DOI: 10.1038/srep40675
PMCID: PMC5233958

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-28084423-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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