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Article

Loss of heterozygosity at the SS receptor type 5 locus in human GH- and TSH-secreting pituitary adenomas.

Journal of endocrinological investigation - 1 Nov 2004

Filopanti M, Ballarè E, Lania A G, Bondioni S, Verga U, Locatelli M, Zavanone L M, Losa M, Gelmini S, Peri A, Orlando C, Beck-Peccoz P, Spada A

Abstract excerpt

SS receptor types 2 and 5 (sst2 and sst5) are involved in the control of secretion and proliferation of normal and tumoral somatotrophs and thyrotrophs. The mechanisms leading to reduced responsiveness to SS analogues in patients with pituitary tumors are poorly understood. The aim of the study was to verify the possible loss of heterozygosity (LOH) at the sst5 gene locus in somatotroph and thyrotroph adenomas by...

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Identifiers

PMID: 15762041
DOI: 10.1007/BF03347536

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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