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Article

Genetic abnormalities of somatostatin receptors in pituitary tumors.

Molecular and cellular endocrinology - 14 May 2008

Lania A, Mantovani G, Spada A

Abstract excerpt

Somatostatin exerts antisecretive and antiproliferative effects on different endocrine cells by acting through a family of G protein-coupled receptors that includes five subtypes (SST1-5). Normal human pituitary and pituitary adenomas have been shown to express almost all SST subtypes, with the exception of SST4. Consistent with the observation that octreotide and other somatostatin analogs bind to SST2 and SST5...

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Source

Identifiers

PMID: 17913341
DOI: 10.1016/j.mce.2007.08.013

Genes

SST

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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