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Truncated somatostatin receptors as new players in somatostatin–cortistatin pathophysiology

1 Mar 2011

Abstract excerpt

Somatostatin (SST) and cortistatin (CORT) act through a family of seven transmembrane domain (TMD) receptors (sst1-5) to govern multiple functions, from growth hormone (GH) secretion to neurotransmission, metabolic homeostasis, gastrointestinal and immune function, and tumor cell growth. Thus, SST analogs are used to treat endocrine/tumoral pathologies. Yet, some SST/CORT actions cannot be explained by their...

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PMID: 21388399
DOI: 10.1111/j.1749-6632.2011.05985.x

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