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Article

Molecular analysis of the somatostatin receptor subtype 2 in human glioma cells.

Brain research. Molecular brain research - 22 Jan 1999

Held-Feindt J, Krisch B, Mentlein R

Abstract excerpt

Gliomas constantly overexpress the receptor subtype SST2 for the inhibitory peptide somatostatin. Since somatostatin or metabolically stable agonists like octreotide have an antiproliferative and antisecretory potential for the treatment of SST2-expressing tumors, we evaluated the molecular integrity of SST2 in gliomas on the DNA, mRNA and protein levels. Sequencing of about 1800 bases from the SST2 gene in nine...

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PMID: 9889335
DOI: 10.1016/s0169-328x(98)00312-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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