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Article

Transcription of SST2 somatostatin receptor gene in human pancreatic cancer cells is altered by single nucleotide promoter polymorphism.

Gastroenterology - 1 Jan 2001

Torrisani J, Bouisson M, Puente E, Capellà G, Laurent-Puig P, Berger A, Vaysse N, Susini C, Buscail L

Abstract excerpt

BACKGROUND & AIMS: The somatostatin receptor SST2 mediates the antiproliferative effect of stable somatostatin analogues. SST2 gene expression is lost in most human pancreatic carcinomas. We investigated the mechanisms that could be involved in this defect. METHODS: SST2 gene structure was investigated by sequencing and restriction fragment length polymorphism. Characterization of the polymorphism was performed...

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Identifiers

PMID: 11208729
DOI: 10.1053/gast.2001.21192

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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