Article
Untangling the effects of codon mutation and amino acid exchangeability.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2005
Yampolsky L Y, Stoltzfus A
Abstract excerpt
Determining the relative contributions of mutation and selection to evolutionary change is a matter of great practical and theoretical significance. In this paper, we examine relative contributions of codon mutation rates and amino acid exchangeability on the frequencies of each type of amino aci...
Topics
- Amino Acid Substitution
- Analysis of Variance
- Codon
- Genetic Variation
- Humans
- Models, Genetic
- Mutation
- Mutation, Missense
- Polymorphism, Single Nucleotide
- Proteins
- Reproducibility of Results