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DEX: an amino acid exchangeability measure for codon substitution modelling and selection inference

2026-03-12

Abstract excerpt

Physicochemically similar amino acids undergo more frequent substitutions compared to dissimilar amino acid pairs. Despite their clear potential, amino acid similarity matrices remain underused for certain molecular evolution applications. One key potential application that is understudied is in quantifying the strength of natural selection based on amino acid substitution patterns. This is partially due to the hi...

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Literature Corpus work
15da930a-5bc8-570a-9f4d-bcc9a016dc83
DOI
10.64898/2026.03.09.710665
Open publication

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