Article
The exchangeability of amino acids in proteins.
Genetics - 1 Aug 2005
Yampolsky Lev Y, Stoltzfus Arlin
Abstract excerpt
The comparative analysis of protein sequences depends crucially on measures of amino acid similarity or distance. Many such measures exist, yet it is not known how well these measures reflect the operational exchangeability of amino acids in proteins, since most are derived by methods that confound a variety of effects, including effects of mutation. In pursuit of a pure measure of exchangeability, we present (1)...
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