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Article

Heterogeneous patterns of CEBPalpha mutation status in the progression of myelodysplastic syndrome and chronic myelomonocytic leukemia to acute myelogenous leukemia.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Mar 2005

Shih Lee-Yung, Huang Chein-Fuang, Lin Tung-Liang, Wu Jin-Hou, Wang Po-Nan, Dunn Po, Kuo Ming-Chung, Tang Tzung-Chih

Abstract excerpt

PURPOSE: We aimed to assess the role of CEBPalpha mutations in the progression of myelodysplastic syndrome (MDS) to acute myelogenous leukemia (AML) and their cooperating mutations. EXPERIMENTAL DESIGN: Mutational analysis of CEBPalpha with direct sequencing for each PCR product was done on matched bone marrow samples obtained from 50 adult patients with MDS at diagnosis and at AML transformation. Cloning...

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Share to CCAAT-Enhancer-Binding Protein-alpha
Share to Cell Transformation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to DNA Mutational Analysis

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Share to Leukemia, Myeloid, Acute

Share to Leukemia, Myelomonocytic, Chronic

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Source

Identifiers

PMID: 15756005
DOI: 10.1158/1078-0432.CCR-04-1932

Genes

FLT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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