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Article

Expression and regulation of C/EBPα in normal myelopoiesis and in malignant transformation.

Blood - 13 Apr 2017

Avellino Roberto, Delwel Ruud

Abstract excerpt

One of the most studied transcription factors in hematopoiesis is the leucine zipper CCAAT-enhancer binding protein α (C/EBPα), which is mainly involved in cell fate decisions for myeloid differentiation. Its involvement in acute myeloid leukemia (AML) is diverse, with patients frequently exhibiting mutations, deregulation of gene expression, or alterations in the function of C/EBPα. In this review, we emphasize...

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Share to CCAAT-Enhancer-Binding Proteins
Share to Cell Transformation, Neoplastic
Share to Gene Expression Regulation, Leukemic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28179278
DOI: 10.1182/blood-2016-09-687822

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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