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Article

CEBPA methylation and mutation in myelodysplastic syndrome.

Medical oncology (Northwood, London, England) - 1 Jul 2015

Wen Xiang-mei, Hu Jia-bo, Yang Jing, Qian Wei, Yao Dong-ming, Deng Zhao-qun, Zhang Ying-ying, Zhu Xiao-wen, Guo Hong, Lin Jiang, Qian Jun

Abstract excerpt

Aberrant methylation of CCAAT/enhancer-binding protein alpha (CEBPA) promoter has been observed in acute myeloid leukemia. However, little is known about CEBPA promoter in myelodysplastic syndrome (MDS). The purpose of this study was to investigate the alteration of CEBPA promoter in MDS patients and further determine the association with CEBPA expression and mutation. CEBPA promoter was significantly methylated...

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Share to Aged, 80 and over
Share to CCAAT-Enhancer-Binding Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Gene Expression Profiling

Share to Gene Expression Regulation, Leukemic

Share to Leukemia, Myeloid, Acute

Share to Myelodysplastic Syndromes

Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 26025484
DOI: 10.1007/s12032-015-0605-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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