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Article

Folding efficiency is rate-limiting in dopamine D4 receptor biogenesis.

The Journal of biological chemistry - 13 May 2005

Van Craenenbroeck Kathleen, Clark Stewart D, Cox Michael J, Oak James N, Liu Fang, Van Tol Hubert H M

Abstract excerpt

Dopamine receptors are G protein-coupled receptors that are critically involved in locomotion, reward, and cognitive processes. The D2 class of dopamine receptors (DRD2, -3, and -4) is the target for antipsychotic medication. DRD4 has been implicated in cognition, and genetic studies have found an association between a highly polymorphic repeat sequence in the human DRD4 coding region and attention deficit...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15755724
DOI: 10.1074/jbc.M414043200

Genes

DRD4
DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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