Article
A hypervariable segment in the human dopamine receptor D4 (DRD4) gene.
Human molecular genetics - 1 Jun 1993
Lichter J B, Barr C L, Kennedy J L, Van Tol H H, Kidd K K, Livak K J
Abstract excerpt
The human dopamine D4 receptor contains a novel polymorphism within the putative third cytoplasmic loop of the protein. The polymorphism is characterized by a varying number of direct imperfect 48-bp repeats in the gene. Pharmacological characterization has suggested that this receptor is the sit...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- Clozapine
- Ethnicity
- Gene Frequency
- Genes
- Genotype
- Haplotypes
- Humans
- Molecular Sequence Data
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Receptors, Dopamine
- Receptors, Dopamine D2
- Receptors, Dopamine D4
- Repetitive Sequences, Nucleic Acid
