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Article

Structure of the D2 dopamine receptor bound to the atypical antipsychotic drug risperidone.

Nature - 8 Mar 2018

Wang Sheng, Che Tao, Levit Anat, Shoichet Brian K, Wacker Daniel, Roth Bryan L

Abstract excerpt

Dopamine is a neurotransmitter that has been implicated in processes as diverse as reward, addiction, control of coordinated movement, metabolism and hormonal secretion. Correspondingly, dysregulation of the dopaminergic system has been implicated in diseases such as schizophrenia, Parkinson's disease, depression, attention deficit hyperactivity disorder, and nausea and vomiting. The actions of dopamine are...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29466326
DOI: 10.1038/nature25758
PMCID: PMC5843546

Genes

DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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